Less than 24 hours after Apple held a special event to unveil the new, record-thin (0.20 inch, the thinnest Apple device yet) iPad Pro with M4 chip inside, which the company says is optimized for AI, it is facing a loud and fast-spreading public backlash to one of its new marquee video advertisements promoting the device -- a spot called "Crush." VentureBeat: The video features a giant, industrial hydraulic press machine -- a device category famous for appearing in viral videos over the last decade-and-a-half -- literally pressing down upon and destroying dozens of other objects and creative instruments, from trumpets to cans of paint. The ad concludes with the press lifting to reveal these objects have somehow been transformed into a new iPad Pro. The metaphor and messaging is pretty obvious: the iPad Pro can subsume and replace all these older legacy instruments and technologies inside of it, and all in a more portable, sleek, and more powerful form factor than ever before.

It's analogous to similar observations and advertisements other fans and creatives have made in the past about how PCs and smartphones replaced nearly all the individual gadgets -- stereo radios/boom boxes, journals, calculators, drawing pads, typewriters, video cameras -- of yore by offering many of their same core capabilities in a smaller, unified, more portable form factor. [...] People are revolted by the bluntness of Apple's metaphor, the destruction of beloved traditional instruments and objects which people hold in high esteem and affix intangible value to for their creative potential, and the overarching and perhaps unintentional messaging that Apple wants to literally flatten creativity and violently crush the creative tools of yesterday in favor of a multi-hundred dollar piece of luxury technology whose operating system and ecosystem of applications it tightly controls and restricts.

AstraZeneca said on Tuesday it had initiated the worldwide withdrawal of its COVID-19 vaccine due to a "surplus of available updated vaccines" since the pandemic. From a report: The company also said it would proceed to withdraw the vaccine Vaxzevria's marketing authorizations within Europe. "As multiple, variant COVID-19 vaccines have since been developed there is a surplus of available updated vaccines," the company said, adding that this had led to a decline in demand for Vaxzevria, which is no longer being manufactured or supplied. According to media reports, the Anglo-Swedish drugmaker has previously admitted in court documents that the vaccine causes side-effects such as blood clots and low blood platelet counts.

The Biden administration is poised to open up a new front in its effort to safeguard U.S. AI from China with preliminary plans to place guardrails around the most advanced AI models, the core software of artificial intelligence systems like ChatGPT, Reuters reported Wednesday. From the report: The Commerce Department is considering a new regulatory push to restrict the export of proprietary or closed source AI models, whose software and the data it is trained on are kept under wraps, three people familiar with the matter said. Any action would complement a series of measures put in place over the last two years to block the export of sophisticated AI chips to China in an effort to slow Beijing's development of the cutting edge technology for military purposes. Even so, it will be hard for regulators to keep pace with the industry's fast-moving developments.

Currently, nothing is stopping U.S. AI giants like Microsoft-backed OpenAI, Alphabet's Google DeepMind and rival Anthropic, which have developed some of the most powerful closed source AI models, from selling them to almost anyone in the world without government oversight. Government and private sector researchers worry U.S. adversaries could use the models, which mine vast amounts of text and images to summarize information and generate content, to wage aggressive cyber attacks or even create potent biological weapons. To develop an export control on AI models, the sources said the U.S. may turn to a threshold contained in an AI executive order issued last October that is based on the amount of computing power it takes to train a model. When that level is reached, a developer must report its AI model development plans and provide test results to the Commerce Department.

An anonymous reader quotes a report from MSN: The US has revoked licenses allowing Huawei to buy semiconductors from Qualcomm and Intel, according to people familiar with the matter, further tightening export restrictions against the Chinese telecom equipment maker. Withdrawal of the licenses affects US sales of chips for use in Huawei phones and laptops, according to the people, who discussed the move on condition of anonymity. House Foreign Affairs Committee Chairman Michael McCaul confirmed the administration's decision in an interview Tuesday. He said the move is key to preventing China from developing advanced AI. "It's blocking any chips sold to Huawei," said McCaul, a Texas Republican who was briefed about the license decisions for Intel and Qualcomm. "Those are two companies we've always worried about being a little too close to China."

While the decision may not affect a significant volume of chips, it underscores the US government's determination to curtail China's access to a broad swathe of semiconductor technology. Officials are also considering sanctions against six Chinese firms that they suspect could supply chips to Huawei, which has been on a US trade restrictions list since 2019. [...] Qualcomm recently said that its business with Huawei is already limited and will soon shrink to nothing. It has been allowed to supply the Chinese company with chips that provide older 4G network connections. It's prohibited from selling ones that allow more advanced 5G access.

Computer models have found that recent heat waves in the north Pacific may be due to a large reduction in aerosols emitted by factories in China. The findings have been published in the Proceedings of the National Academy of Sciences. Phys.Org reports: In this new effort, the research team noted that the onset of the heat waves appeared to follow successful efforts by the Chinese government to reduce aerosol emissions from their country's factories. Beginning around 2010, factories and power generating plants in China began dramatically reducing emissions of aerosols such as sulfate, resulting in much cleaner air. Noting that aerosols can act like mirrors floating in the air, reflecting heat from the sun back into space, and also pointing out that earlier research efforts had suggested that massive reductions of aerosols in one place could lead to warming in other places -- they wondered if reductions of aerosols in China might be playing a role in the heat waves that began happening in the north Pacific.

To find out if that might be the case, the team began collecting data and then input it into 12 different computer climate models. They ran them under two conditions -- one where emissions from East Asia remained as they were over the past several decades and one where they dropped in the way they had in reality. They found that the models with no declines did not cause much change elsewhere, whereas those with aerosol drops showed heat waves occurring in the northeast parts of the Pacific Ocean.

The models also showed why -- as less heat was reflected back into space over China, warming of coastal regions in Asia began, resulting in the development of high-pressure systems. That in turn made low-pressure systems in the middle Pacific more intense. And that resulted in the Aleutian Low growing bigger and moving south which weakened the westerly winds that typically cool the sea surface. The result was hotter conditions.

Renewable energy accounted for more than 30% of the world's electricity for the first time last year, according to climate thinktank Ember. The Guardian reports: Clean electricity has already helped to slow the growth in fossil fuels by almost two-thirds in the past 10 years, according to the report by climate thinktank Ember. It found that renewables have grown from 19% of electricity in 2000 to more than 30% of global electricity last year. Solar was the main supplier of electricity growth, according to Ember, adding more than twice as much new electricity generation as coal in 2023. It was the fastest-growing source of electricity for the 19th consecutive year, and also became the largest source of new electricity for the second year running, after surpassing wind power.

The first comprehensive review of global electricity data covers 80 countries, which represent 92% of the world's electricity demand, as well as historic data for 215 countries. The surge in clean electricity is expected to power a 2% decrease in global fossil fuel generation in the year ahead, according to Ember. [...] World leaders are aiming to grow renewables to 60% of global electricity by 2030 under an agreement struck at the UN's Cop28 climate change conference in December. This would require countries to triple their current renewable electricity capacity in the next six years, which would almost halve power sector emissions.

Lawyers for the defunct cryptocurrency exchange FTX said customers would receive all the money they lost when the firm collapsed in 2022 and receive interest on top of it. "But the recoveries come with a caveat," reports the New York Times. "The amount owed to customers was calculated based on the value of their holdings at the time of FTX's bankruptcy in November 2022. That means customers won't reap the benefits of a recent surge in the crypto market that sent the price of Bitcoin to a record high." From the report: The announcement was a landmark in the attempt to recover the $8 billion in customer assets that disappeared when FTX imploded virtually overnight, setting off a crisis in the crypto industry. Under a plan filed in federal bankruptcy court in Delaware, virtually all FTX's creditors, including hundreds of thousands of ordinary investors who used the exchange to buy and sell cryptocurrencies, would receive cash payments equivalent to 118 percent of the assets they had stored on FTX, the lawyers said. Those payments would flow from a pool of assets that FTX's lawyers have pulled together in the 17 months since the exchange collapsed, the lawyers said. [...] It will take months for the payouts to begin. The plan must be approved by the federal judge overseeing FTX's bankruptcy, John T. Dorsey.

An anonymous reader quotes a report from the Washington Post: A key supplier to the Pentagon and U.S. intelligence agencies is building a $20 million supercomputer with buzzy chipmaker Nvidia to speed deployment of artificial intelligence capabilities across the U.S. federal government, the MITRE think tank said Tuesday. MITRE, a federally funded, not-for-profit research organization that has supplied U.S. soldiers and spies with exotic technical products since the 1950s, says the project could improve everything from Medicare to taxes. "There's huge opportunities for AI to make government more efficient," said Charles Clancy, senior vice president of MITRE. "Government is inefficient, it's bureaucratic, it takes forever to get stuff done. ... That's the grand vision, is how do we do everything from making Medicare sustainable to filing your taxes easier?" [...] The MITRE supercomputer will be based in Ashburn, Va., and should be up and running late this year. [...]

Clancy said the planned supercomputer will run 256 Nvidia graphics processing units, or GPUs, at a cost of $20 million. This counts as a small supercomputer: The world's fastest supercomputer, Frontier in Tennessee, boasts 37,888 GPUs, and Meta is seeking to build one with 350,000 GPUs. But MITRE's computer will still eclipse Stanford's Natural Language Processing Group's 68 GPUs, and will be large enough to train large language models to perform AI tasks tailored for government agencies. Clancy said all federal agencies funding MITRE will be able to use this AI "sandbox." "AI is the tool that is solving a wide range of problems," Clancy said. "The U.S. military needs to figure out how to do command and control. We need to understand how cryptocurrency markets impact the traditional banking sector. ... Those are the sorts of problems we want to solve."

Pam Belluck reports via the New York Times: Scientists are proposing a new way of understanding the genetics of Alzheimer's that would mean that up to a fifth of patients would be considered to have a genetically caused form of the disease. Currently, the vast majority of Alzheimer's cases do not have a clearly identified cause. The new designation, proposed in a study published Monday, could broaden the scope of efforts to develop treatments, including gene therapy, and affect the design of clinical trials. It could also mean that hundreds of thousands of people in the United States alone could, if they chose, receive a diagnosis of Alzheimer's before developing any symptoms of cognitive decline, although there currently are no treatments for people at that stage. The new classification would make this type of Alzheimer's one of the most common genetic disorders in the world, medical experts said.

"This reconceptualization that we're proposing affects not a small minority of people," said Dr. Juan Fortea, an author of the study and the director of the Sant Pau Memory Unit in Barcelona, Spain. "Sometimes we say that we don't know the cause of Alzheimer's disease," but, he said, this would mean that about 15 to 20 percent of cases "can be tracked back to a cause, and the cause is in the genes." The idea involves a gene variant called APOE4. Scientists have long known that inheriting one copy of the variant increases the risk of developing Alzheimer's, and that people with two copies, inherited from each parent, have vastly increased risk.

The new study, published in the journal Nature Medicine, analyzed data from over 500 people with two copies of APOE4, a significantly larger pool than in previous studies. The researchers found that almost all of those patients developed the biological pathology of Alzheimer's, and the authors say that two copies of APOE4 should now be considered a cause of Alzheimer's -- not simply a risk factor. The patients also developed Alzheimer's pathology relatively young, the study found. By age 55, over 95 percent had biological markers associated with the disease. By 65, almost all had abnormal levels of a protein called amyloid that forms plaques in the brain, a hallmark of Alzheimer's. And many started developing symptoms of cognitive decline at age 65, younger than most people without the APOE4 variant.

At the 27th annual Milken Institute Global Conference on Monday, OpenAI COO Brad Lightcap said today's ChatGPT chatbot "will be laughably bad" compared to what it'll be capable of a year from now. "We think we're going to move toward a world where they're much more capable," he added. Business Insider reports: Lightcap says large language models, which people use to help do their jobs and meet their personal goals, will soon be able to take on "more complex work." He adds that AI will have more of a "system relationship" with users, meaning the technology will serve as a "great teammate" that can assist users on "any given problem." "That's going to be a different way of using software," the OpenAI exec said on the panel regarding AI's foreseeable capabilities.

In light of his predictions, Lightcap acknowledges that it can be tough for people to "really understand" and "internalize" what a world with robot assistants would look like. But in the next decade, the COO believes talking to an AI like you would with a friend, teammate, or project collaborator will be the new norm. "I think that's a profound shift that we haven't quite grasped," he said, referring to his 10-year forecast. "We're just scratching the surface on the full kind of set of capabilities that these systems have," he said at the Milken Institute conference. "That's going to surprise us." You can watch/listen to the talk here.

"With all the improvements in car safety over the decades, the recent addition of a plethora of high tech sensors and warnings comes with increased costs," writes longtime Slashdot reader smooth wombat. "And not just to have to have them on your car. Any time you get into an accident, even a minor one, it will most likely require a detailed examination of any sensors which may have been affected and their subsequent realignment, replacement, and calibration." CNN reports: Some vehicles require "dynamic calibration," which means, once the sensors and cameras are back in place, a driver needs to take the vehicle out on real roads for testing. With proper equipment attached the car can, essentially, recalibrate itself as it watches lane lines and other markers. It requires the car to be driven for a set distance at a certain speed but weather and traffic can create problems. "If you're in Chicago or L.A., good luck getting to that speed," said [Hami Ebrahimi, chief commercial officer at Caliber] "or if you're in Seattle or Chicago or New York, with snow, good luck picking up all the road markings."

More commonly, vehicles need "static calibration," which can be done using machinery inside a closed workshop with a flat, level floor. Special targets are set up around the vehicle at set distances according to instructions from the vehicle manufacturer. "The car [views] those targets at those specific distances to recalibrate the world into the car's computer," Ebrahimi said. These kinds of repairs also demand buildings with open space that meet requirements including specific colors and lighting. And it requires special training for employees to perform these sorts of recalibrations, he said

"The change that we've seen in the last five years is greater than we've seen, probably, in the last five decades," said Todd Dillender, chief operating officer of Caliber Collision, one of the biggest auto body repair companies in the United States with more than 1,700 locations across 41 states. [...] With a rapidly changing industry, qualified auto body repair technicians are in short supply, just as they are in the engine repair business. That's also led to upward pressure on pay in the industry as technicians have to be highly qualified and educated, Dillender said. That's good for people who work in the industry, of course, but tougher for those who pay, and for the insurance companies who, in turn, pay for the repairs. A new study from consumer automotive group AAA says the cost to fix sensors and cameras in new vehicles "now accounts for more than a third of the post-crash repair costs," reports CNN. However, "no one, including AAA, recommends not getting these features because of repair costs," since many of them can cut crash rates in half and improve a car's overall safety.

"They're not going to prevent everything," said Greg Brannon, director of automotive engineering at AAA. "And when you are in a crash, there are additional costs so it's sort of the old 'there's no free ride' when it comes to these things."

An anonymous reader quotes a report from Wired: Amazon plans to start flying delivery drones in Arizona this year -- but don't count on them to bring you a refreshing drink on a hot day. The hexacopter can't operate when temperatures top 104 degrees Fahrenheit, or 40 degrees Celsius, the company says, and average daily highs exceed that for three months of the year in Tolleson, the city outside Phoenix where Amazon is preparing to offer aerial deliveries from inside a 7.5-mile radius. The drones can't help with midnight snacks either, because they'll be grounded after sunset. Potentially being inoperable for a quarter of the year might make launching drone deliveries in Tolleson and neighboring desert communities seem like an odd choice. It's far from the first challenge faced by Amazon's much-delayed drone project. The unit is years behind its goals of flying items to customers in under an hour on a regular basis, and a one-time target of 500 million deliveries by 2030 seems distant. Amazon Prime Air has completed just thousands of deliveries, falling behind rivals; Alphabet subsidiary Wing has notched hundreds of thousands of delivery flights and Walmart more than 20,000.

In the California wine country town of Lockeford, where Amazon initially launched drone deliveries, some residents told WIRED last year that they ordered only because Amazon lured them with gift cards. In Arizona, it could be discouraging not being able to rely on drones during those hours when one might not want to venture too far from the comfort of air conditioning. [...] That temperature and other environmental conditions could ground or hamper the drone industry has been known for years. A team from University of Calgary's geography department estimated that on average across the world, drones with limitations similar to Amazon's, including from weather and daylight, would be limited to flying about 2 hours a day. In the world's 100 most populous cities, the average daily flight time would be 6 hours. "Weather is an important and poorly resolved factor that may affect ambitions to expand drone operations," they wrote in a study published in 2021. Heat, in particular, forces motors to work harder to keep drones aloft, and their batteries are only so powerful.

Wayve, a UK-based AI firm focused on developing self-driving car technology, has secured a record $1.05 billion in funding, with Microsoft and Nvidia participating in the round led by SoftBank. According to the BBC, this investment is the largest for an AI company in Europe. The BBC reports: Wayve says the funding will allow it to help build the autonomous cars of the future. [...] Wayve is developing technology intended to power future self-driving vehicles by using what it calls "embodied AI." Unlike AI models carrying out cognitive or generative tasks such as answering questions or creating pictures, this new technology interacts with and learns from real-world surroundings and environments. "[The investment] sends a crucial signal to the market of the strength of the UK's AI ecosystem, and we look forward to watching more AI companies here thrive and scale," said Wayve head Alex Kendall.

For the second time, the disgraced former CEO of Theranos has had her federal prison sentence shortened. In July, it was reduced by two years. Now, 40-year-old Holmes is scheduled for release on August 16, 2032 instead of December 29, 2032 -- a reduction of more than four months. The Guardian reports: People incarcerated in the U.S. can have their sentences shortened for good conduct and for completing rehabilitation programs, such as a substance abuse program. The latest reduction of Holmes's sentence still meets federal sentencing guidelines. Those guidelines mandate that people convicted of federal offenses must serve at least 85% of their sentence, regardless of reductions for good behavior.

In 2022, Holmes was sentenced to 11 years and three months in prison after being convicted on four counts of defrauding investors. She was also ordered to pay $452m in restitution to those she defrauded, but a judge delayed those payments due to Holmes's "limited financial resources." Holmes's lawyers have already begun attempts to get her conviction overturned. Oral arguments for her appeal are set to begin on June 11 in a federal appeals court in San Francisco, California, NBC News reported.